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Proteasomal Degradation of TRIM5α during Retrovirus Restriction
The host protein TRIM5α inhibits retroviral infection at an early post-penetration stage by targeting the incoming viral capsid. While the detailed mechanism of restriction remains unclear, recent studies have implicated the activity of cellular proteasomes in the restriction of retroviral reverse t...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374908/ https://www.ncbi.nlm.nih.gov/pubmed/18497858 http://dx.doi.org/10.1371/journal.ppat.1000074 |