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Sphingomyelin Functions as a Novel Receptor for Helicobacter pylori VacA

The vacuolating cytotoxin (VacA) of the gastric pathogen Helicobacter pylori binds and enters epithelial cells, ultimately resulting in cellular vacuolation. Several host factors have been reported to be important for VacA function, but none of these have been demonstrated to be essential for toxin...

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Detalles Bibliográficos
Autores principales: Gupta, Vijay R., Patel, Hetal K., Kostolansky, Sean S., Ballivian, Roberto A., Eichberg, Joseph, Blanke, Steven R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374909/
https://www.ncbi.nlm.nih.gov/pubmed/18497859
http://dx.doi.org/10.1371/journal.ppat.1000073