Fibrinogen Binding Sites P(336) and Y(338) of Clumping Factor A Are Crucial for Staphylococcus aureus Virulence

We have earlier shown that clumping factor A (ClfA), a fibrinogen binding surface protein of Staphylococcus aureus, is an important virulence factor in septic arthritis. When two amino acids in the ClfA molecule, P(336) and Y(338), were changed to serine and alanine, respectively, the fibrinogen bin...

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Detalles Bibliográficos
Autores principales: Josefsson, Elisabet, Higgins, Judy, Foster, Timothy J., Tarkowski, Andrej
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374910/
https://www.ncbi.nlm.nih.gov/pubmed/18493318
http://dx.doi.org/10.1371/journal.pone.0002206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374910/
https://www.ncbi.nlm.nih.gov/pubmed/18493318
http://dx.doi.org/10.1371/journal.pone.0002206

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