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Fibrinogen Binding Sites P(336) and Y(338) of Clumping Factor A Are Crucial for Staphylococcus aureus Virulence
We have earlier shown that clumping factor A (ClfA), a fibrinogen binding surface protein of Staphylococcus aureus, is an important virulence factor in septic arthritis. When two amino acids in the ClfA molecule, P(336) and Y(338), were changed to serine and alanine, respectively, the fibrinogen bin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374910/ https://www.ncbi.nlm.nih.gov/pubmed/18493318 http://dx.doi.org/10.1371/journal.pone.0002206 |