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Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis

INTRODUCTION: Aberrant microenvironment and endoplasmic reticulum (ER) stress are associated with solid-tumor progression. Stress proteins, like heat shock proteins and glucose-regulated proteins, are frequently overexpressed in human tumors. It has been reported that derlin-1 is involved in ER stre...

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Detalles Bibliográficos
Autores principales: Wang, Jiao, Hua, Hui, Ran, Yuliang, Zhang, Hongyin, Liu, Weiping, Yang, Zhihua, Jiang, Yangfu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374959/
https://www.ncbi.nlm.nih.gov/pubmed/18205950
http://dx.doi.org/10.1186/bcr1849