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Suppression of adenine nucleotide translocase-2 by vector-based siRNA in human breast cancer cells induces apoptosis and inhibits tumor growth in vitro and in vivo

INTRODUCTION: Adenine nucleotide translocator (ANT) 2 is highly expressed in proliferative cells, and ANT2 induction in cancer cells is known to be directly associated with glycolytic metabolisms and carcinogenesis. In addition, ANT2 repression results in the growth arrest of human cells, implying t...

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Detalles Bibliográficos
Autores principales: Jang, Ji-Young, Choi, Yun, Jeon, Yoon-Kyung, Kim, Chul-Woo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374967/
https://www.ncbi.nlm.nih.gov/pubmed/18267033
http://dx.doi.org/10.1186/bcr1857