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ESR1 and EGF genetic variation in relation to breast cancer risk and survival

INTRODUCTION: Oestrogen exposure is a central factor in the development of breast cancer. Oestrogen receptor alpha (ESR1) is the main mediator of oestrogen effect in breast epithelia and has also been shown to be activated by epidermal growth factor (EGF). We sought to determine if common genetic va...

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Detalles Bibliográficos
Autores principales: Einarsdóttir, Kristjana, Darabi, Hatef, Li, Yi, Low, Yen Ling, Li, Yu Qing, Bonnard, Carine, Sjölander, Arvid, Czene, Kamila, Wedrén, Sara, Liu, Edison T, Hall, Per, Humphreys, Keith, Liu, Jianjun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374971/
https://www.ncbi.nlm.nih.gov/pubmed/18271972
http://dx.doi.org/10.1186/bcr1861