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The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression
BACKGROUND: MicroRNAs (miRNAs) are small noncoding RNAs that bind mRNA target transcripts and repress gene expression. They have been implicated in multiple diseases, such as cancer, but the mechanisms of this involvement are not well understood. Given the complexity and degree of interactions betwe...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374997/ https://www.ncbi.nlm.nih.gov/pubmed/17697356 http://dx.doi.org/10.1186/gb-2007-8-8-r166 |