InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale

We propose InSite, a computational method that integrates high-throughput protein and sequence data to infer the specific binding regions of interacting protein pairs. We compared our predictions with binding sites in Protein Data Bank and found significantly more binding events occur at sites we pr...

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Detalles Bibliográficos
Autores principales: Wang, Haidong, Segal, Eran, Ben-Hur, Asa, Li, Qian-Ru, Vidal, Marc, Koller, Daphne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375030/
https://www.ncbi.nlm.nih.gov/pubmed/17868464
http://dx.doi.org/10.1186/gb-2007-8-9-r192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375030/
https://www.ncbi.nlm.nih.gov/pubmed/17868464
http://dx.doi.org/10.1186/gb-2007-8-9-r192

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