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Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

BACKGROUND: Increased dietary cholesterol intake is associated with atherosclerosis. Atherosclerosis development requires a lipid and an inflammatory component. It is unclear where and how the inflammatory component develops. To assess the role of the liver in the evolution of inflammation, we treat...

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Detalles Bibliográficos
Autores principales: Kleemann, Robert, Verschuren, Lars, van Erk, Marjan J, Nikolsky, Yuri, Cnubben, Nicole HP, Verheij, Elwin R, Smilde, Age K, Hendriks, Henk FJ, Zadelaar, Susanne, Smith, Graham J, Kaznacheev, Valery, Nikolskaya, Tatiana, Melnikov, Anton, Hurt-Camejo, Eva, van der Greef, Jan, van Ommen, Ben, Kooistra, Teake
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375038/
https://www.ncbi.nlm.nih.gov/pubmed/17892536
http://dx.doi.org/10.1186/gb-2007-8-9-r200