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The topology of plasminogen binding and activation on the surface of human breast cancer cells

The urokinase-dependent activation of plasminogen by breast cancer cells plays an important role in metastasis. We have previously shown that the metastatic breast cancer cell line MDA-MB-231 over-expresses urokinase and binds and efficiently activates plasminogen at the cell surface compared to non...

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Detalles Bibliográficos
Autores principales: Andronicos, N M, Ranson, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375062/
https://www.ncbi.nlm.nih.gov/pubmed/11556845
http://dx.doi.org/10.1054/bjoc.2001.2022