DNA damage-induced cell cycle checkpoints involve both p53-dependent and -independent pathways: role of telomere repeat binding factor 2

Treatment of colon cancer cells with MNNG causes DNA damage with reduced telomeric signals in a p53-dependent manner, but increased cell cycle arrest in S-G(2)/M by both p53-dependent and independent mechanisms. Results also indicate that cellular levels of TRF2 may play a critical role in MNNG-indu...

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Detalles Bibliográficos
Autores principales: Narayan, S, Jaiswal, A S, Multani, A S, Pathak, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375064/
https://www.ncbi.nlm.nih.gov/pubmed/11556843
http://dx.doi.org/10.1054/bjoc.2001.2002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375064/
https://www.ncbi.nlm.nih.gov/pubmed/11556843
http://dx.doi.org/10.1054/bjoc.2001.2002

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