Cargando…

Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: an active mode of immune evasion in colon cancer

Expression of membrane-bound Fas ligand (mFasL) on colon cancer cells serves as a potential mechanism to inhibit host immune function by inducing apoptosis of host lymphocytes. Membrane-bound FasL can be cleaved and released as a soluble mediator (sFasL), which may spread the apoptosis induction eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, E, Chen, J, Ouyang, N, Su, F, Wang, M, Heemann, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375090/
https://www.ncbi.nlm.nih.gov/pubmed/11592778
http://dx.doi.org/10.1054/bjoc.2001.2042