The Proto-Oncogene Int6 Is Essential for Neddylation of Cul1 and Cul3 in Drosophila

Int6 is a proto-oncogene implicated in various types of cancer, but the mechanisms underlying its activity are not clear. Int6 encodes a subunit of the eukaryotic translation initiation factor 3, and interacts with two related complexes, the proteasome, whose activity is regulated by Int6 in S. pomb...

Descripción completa

Detalles Bibliográficos
Autores principales: Rencus-Lazar, Sigal, Amir, Yaniv, Wu, Junetai, Chien, Cheng-Ting, Chamovitz, Daniel A., Segal, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375110/
https://www.ncbi.nlm.nih.gov/pubmed/18493598
http://dx.doi.org/10.1371/journal.pone.0002239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375110/
https://www.ncbi.nlm.nih.gov/pubmed/18493598
http://dx.doi.org/10.1371/journal.pone.0002239

Ejemplares similares