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The Proto-Oncogene Int6 Is Essential for Neddylation of Cul1 and Cul3 in Drosophila
Int6 is a proto-oncogene implicated in various types of cancer, but the mechanisms underlying its activity are not clear. Int6 encodes a subunit of the eukaryotic translation initiation factor 3, and interacts with two related complexes, the proteasome, whose activity is regulated by Int6 in S. pomb...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375110/ https://www.ncbi.nlm.nih.gov/pubmed/18493598 http://dx.doi.org/10.1371/journal.pone.0002239 |