Using an evolutionary algorithm and parallel computing for haplotyping in a general complex pedigree with multiple marker loci

BACKGROUND: Haplotype reconstruction is important in linkage mapping and association mapping of quantitative trait loci (QTL). One widely used statistical approach for haplotype reconstruction is simulated annealing (SA), implemented in SimWalk2. However, the algorithm needs a very large number of s...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hong, Van der Werf, Julius HJ, Kinghorn, Brian P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375132/
https://www.ncbi.nlm.nih.gov/pubmed/18405361
http://dx.doi.org/10.1186/1471-2105-9-189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375132/
https://www.ncbi.nlm.nih.gov/pubmed/18405361
http://dx.doi.org/10.1186/1471-2105-9-189

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