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Using an evolutionary algorithm and parallel computing for haplotyping in a general complex pedigree with multiple marker loci
BACKGROUND: Haplotype reconstruction is important in linkage mapping and association mapping of quantitative trait loci (QTL). One widely used statistical approach for haplotype reconstruction is simulated annealing (SA), implemented in SimWalk2. However, the algorithm needs a very large number of s...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375132/ https://www.ncbi.nlm.nih.gov/pubmed/18405361 http://dx.doi.org/10.1186/1471-2105-9-189 |