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Proteochemometric modeling of HIV protease susceptibility
BACKGROUND: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated HIV strains to antiviral agents would provide substantial clinical benefit as well as facilitate the development of new c...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375133/ https://www.ncbi.nlm.nih.gov/pubmed/18402661 http://dx.doi.org/10.1186/1471-2105-9-181 |