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Proteochemometric modeling of HIV protease susceptibility

BACKGROUND: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated HIV strains to antiviral agents would provide substantial clinical benefit as well as facilitate the development of new c...

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Detalles Bibliográficos
Autores principales:	Lapins, Maris, Eklund, Martin, Spjuth, Ola, Prusis, Peteris, Wikberg, Jarl ES
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375133/ https://www.ncbi.nlm.nih.gov/pubmed/18402661 http://dx.doi.org/10.1186/1471-2105-9-181

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