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Analysis of the TSC1and TSC2genes in sporadic renal cell carcinomas

The genetic events involved in the aetiology of non-clear-cell renal cell carcinoma (RCC) and a proportion of clear cell RCC remain to be defined. Germline mutations of the TSC1and TSC2genes cause tuberous sclerosis (TSC), a multi-system hamartoma syndrome that is also associated with RCC. We assess...

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Detalles Bibliográficos
Autores principales: Parry, L, Maynard, J H, Patel, A, Clifford, S C, Morrissey, C, Maher, E R, Cheadle, J P, Sampson, J R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375153/
https://www.ncbi.nlm.nih.gov/pubmed/11710839
http://dx.doi.org/10.1054/bjoc.2001.2072