Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression

Mxi1 is a Mad family member that plays a role in cell proliferation and differentiation. To test the role of Mxi1 on tumorigenesis of glioma cells we transfected a CMV-driven MXI1 cDNA in U87 human glioblastoma cells. Two clones were isolated expressing MXI1 levels 18- and 3.5-fold higher than wild-...

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Detalles Bibliográficos
Autores principales: Manni, I, Tunici, P, Cirenei, N, Albarosa, R, Colombo, B M, Roz, L, Sacchi, A, Piaggio, G, Finocchiaro, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375210/
https://www.ncbi.nlm.nih.gov/pubmed/11875718
http://dx.doi.org/10.1038/sj.bjc.6600065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375210/
https://www.ncbi.nlm.nih.gov/pubmed/11875718
http://dx.doi.org/10.1038/sj.bjc.6600065

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