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Abnormal FHIT expression profiles in cervical intraepithelial neoplastic (CIN) lesions

Abnormal fragile histidine triad transcripts were found in 20–30% of CIN2/3 lesions and 11% of normal cervical biopsies by RT–PCR. Bi-allelic loss of the fragile histidine triad gene and the loss of fragile histidine triad protein expression detectable by immunochemical staining with a polyclonal fr...

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Detalles Bibliográficos
Autores principales: Terry, G, Ho, L, Londesborough, P, Cuzick, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375220/
https://www.ncbi.nlm.nih.gov/pubmed/11875703
http://dx.doi.org/10.1038/sj.bjc.6600077