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No germline mutations in CDKN2A (p16) in patients with squamous cell cancer of the head and neck and second primary tumours

There is increasing evidence that predisposition to some cancers has a genetic component. There is a high incidence of loss of heterozygosity on chromosome 9, in the region of tumour suppressor gene CDKN2A (also known as p16), in sporadic squamous cell cancer of the head and neck (SCCHN). To investi...

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Detalles Bibliográficos
Autores principales: Jefferies, S, Edwards, S M, Hamoudi, R A, A'Hern, R, Foulkes, W, Goldgar, D, Eeles, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375247/
https://www.ncbi.nlm.nih.gov/pubmed/11720478
http://dx.doi.org/10.1054/bjoc.2001.2068