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Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2

Traditional clinicopathological features do not predict which patients will develop chemotherapy resistance. The TP53 gene is frequently altered in ovarian cancer but its prognostic implications are controversial. Little is known on the impact of TP53-downstream genes on prognosis. Using molecular a...

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Detalles Bibliográficos
Autores principales: Schuyer, M, Burg, M E L van der, Henzen-Logmans, S C, Fieret, J H, Klijn, J G M, Look, M P, Foekens, J A, Stoter, G, Berns, E M J J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375252/
https://www.ncbi.nlm.nih.gov/pubmed/11720475
http://dx.doi.org/10.1054/bjoc.2001.2101