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Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells

The effects of vinorelbine and paclitaxel on the activity of extracellular signal-regulated protein kinase2 (ERK2), a member of MAP kinase, and its role in the induction of bcl-2 phosphorylation and apoptosis were evaluated in MCF-7 cells. We demonstrated that ERK2 was activated rapidly by vinorelbi...

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Detalles Bibliográficos
Autores principales: Liu, X M, Wang, L G, Kreis, W, Budman, D R, Adams, L M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375254/
https://www.ncbi.nlm.nih.gov/pubmed/11720482
http://dx.doi.org/10.1054/bjoc.2001.2107