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Phenotypic characteristics of colo-rectal cancer in I1307K APC germline mutation carriers compared with sporadic cases

The I1307K APC germline mutation is associated with an increased risk to colo-rectal cancer (CRC). Whether and to what extent the phenotype of CRC in mutation carriers differs from sporadic cases, remains unknown. To gain insight into this issue, we analysed 307 unselected Israeli patients with CRC,...

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Detalles Bibliográficos
Autores principales: Figer, A, Shtoyerman-Chen, R, Tamir, A, Geva, R, Irmin, L, Flex, D, Theodor, L, Sulkes, A, Sadetzki, S, Bar-Meir, S, Friedman, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375261/
https://www.ncbi.nlm.nih.gov/pubmed/11720476
http://dx.doi.org/10.1054/bjoc.2001.2093