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Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation
Many drugs and xenobiotics are lipophilic and they should be transformed into more polar water soluble compounds to be excreted. Cimetidine inhibits cytochrome P450. The aim of this study was to investigate the preventive and/or reversal action of cimetidine on cytochrome P450 induction and other me...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375263/ https://www.ncbi.nlm.nih.gov/pubmed/11870548 http://dx.doi.org/10.1038/sj.bjc.6600102 |