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Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation

Many drugs and xenobiotics are lipophilic and they should be transformed into more polar water soluble compounds to be excreted. Cimetidine inhibits cytochrome P450. The aim of this study was to investigate the preventive and/or reversal action of cimetidine on cytochrome P450 induction and other me...

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Detalles Bibliográficos
Autores principales:	Caballero, F, Gerez, E, Batlle, A, Vazquez, E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375263/ https://www.ncbi.nlm.nih.gov/pubmed/11870548 http://dx.doi.org/10.1038/sj.bjc.6600102

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