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Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma has a median survival of less than 6 months from diagnosis. This is due to the difficulty in early diagnosis, the aggressive biological behaviour of the tumour and a lack of effective therapies for advanced disease. Mammalian heparanase is a heparan-sulphate proteogl...

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Detalles Bibliográficos
Autores principales: Rohloff, J, Zinke, J, Schoppmeyer, K, Tannapfel, A, Witzigmann, H, Mössner, J, Wittekind, C, Caca, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375333/
https://www.ncbi.nlm.nih.gov/pubmed/11953884
http://dx.doi.org/10.1038/sj.bjc.6600232