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Preclinical evaluation of the antiproliferative potential of STI571 in Hodgkin's disease
STI571 is a selective tyrosine kinase inhibitor with proven therapeutic potential in malignancies expressing c-kit. A strong c-kit and stem cell factor expression was detected in the Hodgkin and Reed Sternberg cell line L1236, but not in 20 primary cases of classical Hodgkin's disease. Prolifer...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375346/ https://www.ncbi.nlm.nih.gov/pubmed/11953894 http://dx.doi.org/10.1038/sj.bjc.6600243 |