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Effective treatment of experimental U-87MG human glioblastoma in nude mice with a targeted cytotoxic bombesin analogue, AN-215

Some brain tumours, such as glioblastomas express high levels of receptors for bombesin/gastrin releasing peptide. We investigated whether bombesin/gastrin releasing peptide receptors found in glioblastoma cell lines can be utilised for targeting of a cytotoxic bombesin analogue, AN-215 consisting o...

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Detalles Bibliográficos
Autores principales: Szereday, Z, Schally, A V, Nagy, A, Plonowski, A, Bajo, A M, Halmos, G, Szepeshazi, K, Groot, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375353/
https://www.ncbi.nlm.nih.gov/pubmed/11953892
http://dx.doi.org/10.1038/sj.bjc.6600235