Cirrhotic livers reveal genetic changes in the MDM2-P14ARF system of cell cycle regulators

The genesis of hepatocellular carcinoma is promoted by changes in the regulatory MDM2-P14ARF system. The incidence of such changes has to date not been analysed in non-tumourous livers showing regenerative proliferation. In the present study, 24 cirrhotic livers of alcohol-, autoimmue disorder- or H...

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Detalles Bibliográficos
Autores principales: Schlott, T, Scharf, J G, Gorzel, C, Middel, P, Spring, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375354/
https://www.ncbi.nlm.nih.gov/pubmed/11953887
http://dx.doi.org/10.1038/sj.bjc.6600238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375354/
https://www.ncbi.nlm.nih.gov/pubmed/11953887
http://dx.doi.org/10.1038/sj.bjc.6600238

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