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The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome c release in breast cancer cells
Bisphosphonates are well established in the management of cancer-induced bone disease. Recent studies have indicated that these compounds have direct inhibitory effects on cultured human breast cancer cells. Nitrogen-containing bisphosphonates including zoledronic acid have been shown to induce apop...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375368/ https://www.ncbi.nlm.nih.gov/pubmed/11986784 http://dx.doi.org/10.1038/sj.bjc.6600297 |