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Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles

BACKGROUND: It is expected that prolonged circulation of anticancer drugs will increase their anticancer activity while decreasing their toxic side effects. The purpose of this study was to prepare 5-fluorouracil (5-FU) loaded block copolymers, with poly(γ-benzyl-L-glutamate) (PBLG) as the hydrophob...

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Detalles Bibliográficos
Autores principales: Li, Su, Wang, Anxun, Jiang, Wenqi, Guan, Zhongzhen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375900/
https://www.ncbi.nlm.nih.gov/pubmed/18412945
http://dx.doi.org/10.1186/1471-2407-8-103