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Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles
BACKGROUND: It is expected that prolonged circulation of anticancer drugs will increase their anticancer activity while decreasing their toxic side effects. The purpose of this study was to prepare 5-fluorouracil (5-FU) loaded block copolymers, with poly(γ-benzyl-L-glutamate) (PBLG) as the hydrophob...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375900/ https://www.ncbi.nlm.nih.gov/pubmed/18412945 http://dx.doi.org/10.1186/1471-2407-8-103 |