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Gene transfer of Hodgkin cell lines via multivalent anti-CD30 scFv displaying bacteriophage

BACKGROUND: The display of binding ligands, such as recombinant antibody fragments, on the surface of filamentous phage makes it possible to specifically attach these phage particles to target cells. After uptake of the phage, their internal single-stranded DNA is processed by the host cell, which a...

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Detalles Bibliográficos
Autores principales: Chung, Yoon-Suk A, Sabel, Katja, Krönke, Martin, Klimka, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375901/
https://www.ncbi.nlm.nih.gov/pubmed/18416816
http://dx.doi.org/10.1186/1471-2199-9-37