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APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

BACKGROUND: The objective of this study was to analyze factors influencing the risk and timing of Alzheimer's disease (AD) in central Norway. The APOE ε4 allele is the only consistently identified risk factor for late onset Alzheimer's disease (LOAD). We have described the allele frequenci...

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Detalles Bibliográficos
Autores principales: Sando, Sigrid B, Melquist, Stacey, Cannon, Ashley, Hutton, Michael L, Sletvold, Olav, Saltvedt, Ingvild, White, Linda R, Lydersen, Stian, Aasly, Jan O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375917/
https://www.ncbi.nlm.nih.gov/pubmed/18416843
http://dx.doi.org/10.1186/1471-2377-8-9