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Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4(pos)CD25(high) T Cells for Immunotherapy

BACKGROUND: Regulatory T cell (Treg) based immunotherapy is a potential treatment for several immune disorders. By now, this approach proved successful in preclinical animal transplantation and auto-immunity models. In these models the success of Treg based immunotherapy crucially depends on the ant...

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Detalles Bibliográficos
Autores principales: Peters, Jorieke H., Hilbrands, Luuk B., Koenen, Hans J. P. M., Joosten, Irma
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376059/
https://www.ncbi.nlm.nih.gov/pubmed/18493605
http://dx.doi.org/10.1371/journal.pone.0002233