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Cytostatic potential of novel agents that inhibit the regulation of intracellular pH
Cells within the acidic extracellular environment of solid tumours maintain their intracellular pH (pHi) through the activity of membrane-based ion exchange mechanisms including the Na(+)/H(+) antiport and the Na(+)-dependent Cl(−)/HCO(3)(−) exchanger. Inhibition of these regulatory mechanisms has b...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376112/ https://www.ncbi.nlm.nih.gov/pubmed/12107849 http://dx.doi.org/10.1038/sj.bjc.6600424 |