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Microsatellite instability and intratumoural heterogeneity in 100 right-sided sporadic colon carcinomas
Microsatellite instability has been proposed as an alternative pathway of colorectal carcinogenesis. The aim of this study was to evaluate the interest of immunohistochemistry as a new tool for highlighting mismatch repair deficiency and to compare the results with a PCR-based microsatellite assay....
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376141/ https://www.ncbi.nlm.nih.gov/pubmed/12177776 http://dx.doi.org/10.1038/sj.bjc.6600474 |