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Elevated c-Src is linked to altered cell–matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

Elevated expression and/or activity of c-Src, the prototype of the Src family of protein tyrosine kinases, is associated with the development of human colon cancer. However, despite the known pleiotropic effects of these kinases in promoting (a) cell growth downstream of growth factor receptors, and...

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Detalles Bibliográficos
Autores principales: Jones, R J, Avizienyte, E, Wyke, A W, Owens, D W, Brunton, V G, Frame, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376185/
https://www.ncbi.nlm.nih.gov/pubmed/12402152
http://dx.doi.org/10.1038/sj.bjc.6600594