Regulation of a rat VL30 element in human breast cancer cells in hypoxia and anoxia: role of HIF-1

Novel approaches to cancer gene therapy currently exploit tumour hypoxia to achieve transcriptional targeting using oxygen-regulated enhancer elements called hypoxia response elements. The activity of such elements in hypoxic cells is directly dependent on upregulation of the hypoxia-inducible trans...

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Detalles Bibliográficos
Autores principales: Ameri, K, Burke, B, Lewis, C E, Harris, A L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376195/
https://www.ncbi.nlm.nih.gov/pubmed/12402159
http://dx.doi.org/10.1038/sj.bjc.6600576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376195/
https://www.ncbi.nlm.nih.gov/pubmed/12402159
http://dx.doi.org/10.1038/sj.bjc.6600576

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