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Regulation of a rat VL30 element in human breast cancer cells in hypoxia and anoxia: role of HIF-1
Novel approaches to cancer gene therapy currently exploit tumour hypoxia to achieve transcriptional targeting using oxygen-regulated enhancer elements called hypoxia response elements. The activity of such elements in hypoxic cells is directly dependent on upregulation of the hypoxia-inducible trans...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376195/ https://www.ncbi.nlm.nih.gov/pubmed/12402159 http://dx.doi.org/10.1038/sj.bjc.6600576 |