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CHEK2 variants in susceptibility to breast cancer and evidence of retention of the wild type allele in tumours
We have recently shown that the CHEK2*1100delC mutation acts as a low penetrance breast cancer susceptibility allele. To investigate if other CHEK2 variants confer an increased risk of breast cancer, we have screened an affected individual with breast cancer from 68 breast cancer families. Five of t...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376278/ https://www.ncbi.nlm.nih.gov/pubmed/12454775 http://dx.doi.org/10.1038/sj.bjc.6600637 |