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Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases

Butyrate, produced in the colon by fermentation of dietary fibre, induces apoptosis in colon adenoma and cancer cell lines, which may contribute to protection against colorectal cancer. However, butyrate is present in the colon along with other dietary factors, including unconjugated bile acids, whi...

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Detalles Bibliográficos
Autores principales: McMillan, L, Butcher, S K, Pongracz, J, Lord, J M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376332/
https://www.ncbi.nlm.nih.gov/pubmed/12618885
http://dx.doi.org/10.1038/sj.bjc.6600793