Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer

Capecitabine is an oral prodrug of 5-fluorouracil (FU). Since FU concentrations achieved in malignant lesions are an important determinant of efficacy, we investigated the intratumoral transcapillary transfer of capecitabine and its metabolites in vivo. A total of 10 patients with skin metastases fr...

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Detalles Bibliográficos
Autores principales: Mader, R M, Schrolnberger, C, Rizovski, B, Brunner, M, Wenzel, C, Locker, G, Eichler, H G, Mueller, M, Steger, G G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376334/
https://www.ncbi.nlm.nih.gov/pubmed/12618890
http://dx.doi.org/10.1038/sj.bjc.6600809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376334/
https://www.ncbi.nlm.nih.gov/pubmed/12618890
http://dx.doi.org/10.1038/sj.bjc.6600809

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