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p53 protein regulates the effects of amifostine on apoptosis, cell cycle progression, and cytoprotection
To determine the role of p53 protein on the cellular effects of amifostine, we used molecularly engineered HCT116 colon cancer cells in which the p53 gene was inactivated by targeted homologous recombination or p53 protein was degraded by high-level expression of papillomavirus E6 protein. Amifostin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376343/ https://www.ncbi.nlm.nih.gov/pubmed/12618886 http://dx.doi.org/10.1038/sj.bjc.6600779 |