Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis

Insulin-like growth factor (IGF)-2 is overexpressed in hepatocellular carcinoma and accompanying dysplastic lesions. IGF-2 signalling is mediated through IGF-1 receptor (IGF-1R), while mannose 6-phosphate/insulin-like growth factor-2 receptor (M6P/IGF-2R) controls pericellular levels of free IGF-2....

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Detalles Bibliográficos
Autores principales: Sedlaczek, N, Hasilik, A, Neuhaus, P, Schuppan, D, Herbst, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376349/
https://www.ncbi.nlm.nih.gov/pubmed/12618883
http://dx.doi.org/10.1038/sj.bjc.6600777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376349/
https://www.ncbi.nlm.nih.gov/pubmed/12618883
http://dx.doi.org/10.1038/sj.bjc.6600777

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