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α-Tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-κB activation

Activation of nuclear factor-κB (NF-κB) can interfere with induction of apoptosis triggered by the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL; Apo2L). Therefore, agents that suppress NF-κB activation may sensitise cells to TRAIL-dependent apoptosis. Exposure of Jurkat cells to T...

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Detalles Bibliográficos
Autores principales: Dalen, H, Neuzil, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376774/
https://www.ncbi.nlm.nih.gov/pubmed/12556975
http://dx.doi.org/10.1038/sj.bjc.6600683