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Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro

Platinum-based chemotherapy is the main treatment element to achieve cure for patients with metastatic germ cell tumours. Drug resistance in testicular germ cell tumours (TGCTs) is rare and the reasons are not fully understood. While recent investigations have indicated decreased efficacy of chemoth...

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Detalles Bibliográficos
Autores principales: Koch, S, Mayer, F, Honecker, F, Schittenhelm, M, Bokemeyer, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376846/
https://www.ncbi.nlm.nih.gov/pubmed/14647149
http://dx.doi.org/10.1038/sj.bjc.6601375