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DNA topoisomerase IIα expression and the response toprimary chemotherapy in breast cancer
The α isoform of Topoisomerase IIα (Topo IIα) is a proliferation marker as well as a target for several chemotherapeutic agents such as anthracyclines. In vitro studies have demonstrated the relationship between the Topo IIα expression level and chemosensitivity of target cancer cells. To verify thi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376904/ https://www.ncbi.nlm.nih.gov/pubmed/12915875 http://dx.doi.org/10.1038/sj.bjc.6601185 |